UV-endonuclease from calf thymus with specificity toward pyrimidine dimers in DNA.

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Pyrimidine dimers in UV-irradiated poly dI:dC.

I Dulbecco, R., and M. Vogt, these PROCEEDINGS, 50, 236 (1963). 2Weil, R., and J. Vinograd, these PROCEEDINGS, 50, 730 (1963). 3 Crawford, L. V., and P. H. Black, Virology, 24, 388 (1964). 4Weil, R., these PROCEEDINGS, 49, 480 (1963). 5 Crawford, L. V., R. Dulbecco, M. Fried, L. Montagnier, and M. Stoker, these PROCEEDINGS, 52, 148 (1964). 6 Winocour, E., Virology, 19, 158 (1963). Murikami, W.,...

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Four different DNA helicases from calf thymus.

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Thermodynamic study of interaction between phthalocyanines with calf thymus DNA

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DNA polymerase lambda from calf thymus preferentially replicates damaged DNA.

A new gene (POLL), has been identified encoding the novel DNA polymerase lambda and mapped to mouse chromosome 19 and at human chromosome 10. DNA polymerase lambda contains all the critical residues involved in DNA binding, nucleotide binding, nucleotide selection, and catalysis of DNA polymerization and has been assigned to family X based on sequence homology with polymerase beta, lambda, mu, ...

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UVA generates pyrimidine dimers in DNA directly.

There is increasing evidence that UVA radiation, which makes up approximately 95% of the solar UV light reaching the Earth's surface and is also commonly used for cosmetic purposes, is genotoxic. However, in contrast to UVC and UVB, the mechanisms by which UVA produces various DNA lesions are still unclear. In addition, the relative amounts of various types of UVA lesions and their mutagenic si...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1979

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.76.8.3746